asked a question about today's featured product.
"How are effects on liver?"
The severity of liver damage from ultradrol depends on factors like dosage, duration, and individual sensitivity.
Ultradrol's high hepatotoxicity is primarily due to its chemical structure:
C17-alpha alkylation: This chemical modification allows the steroid to survive the "first-pass" metabolism by the liver, making it highly orally available. However, this same process is what places immense stress on the liver, as it cannot efficiently break down the compound.
Symptoms and severity of liver damage
Potential liver effects range from mild to life-threatening and may include:
Elevated liver enzymes: Users often experience elevated alanine transaminase (ALT) and aspartate transaminase (AST), which are indicators of liver injury.
Cholestasis: This is an impairment of bile flow from the liver, leading to symptoms like jaundice (yellowing of the skin/eyes), dark urine, and pale stools. Severe cases have been linked to Ultradrol (methylstenbolone) use.
Hepatocellular injury: In some instances, the damage can be more severe, causing direct injury to liver cells.
Hepatitis: Case studies have linked Ultradrol (methylstenbolone) use to cholestatic hepatitis, an inflammatory condition of the liver.
Peliosis hepatis: A rare vascular condition where blood-filled cysts form in the liver. It is associated with long-term use of C17-alpha alkylated steroids.
Liver tumors: Long-term use of anabolic steroids has been associated with the development of hepatic tumors, including hepatic adenomas and hepatocellular carcinoma.
Liver failure: In extreme cases, Ultradrol can cause liver failure, which may require a transplant.
before using any oral need baseline labs.
for liver I don't mean just ALT/AST, creatine and eGFR. (see why below) should include GGT.
presuming labs are clear. take organ support.
1800mg of NAC per day.
“N-Acetylcysteine replenishes intracellular glutathione stores and has been shown to attenuate hepatocellular damage in models of toxic liver injury.” — Ates et al., Hepatology (Ates, Hepatology)
1000mg of tudca per day.
“TUDCA exerts cytoprotective effects on hepatocytes and biliary epithelial cells, and can improve markers of liver injury in cholestatic conditions.” — Beuers et al., Journal of Hepatology (Beuers, J Hepatol)
1000mg of curcumin per day.
“Curcumin attenuates liver injury through modulation of oxidative stress and inflammatory pathways, and has shown hepatoprotective effects in various experimental models.” — Farzaei et al., Phytotherapy Research (Farzaei, Phytother Res)
"liver function evaluation must extend beyond conventional ALT/AST testing, as intense training can elevate these transaminases (enzymes that play a crucial role in the metabolism of amino acids) independent of hepatotoxicity. y-glutamyltransferase (GGT) provides superior hepatic health assessment. Creatine kinase (CK) is similarly affected by muscular work, as is creatinine and eGFR that's a function of it. More selective testing helps differentiate muscle-derived enzyme elevations from genuine hepatic stress." type ii-x
also consider liver and kidney ultrasound imaging annually.
CHECK ENGINE LIGHT is on if you have the following
Fatigue or unusual lethargy
Loss of appetite
Nausea or digestive discomfort
Itching (pruritus) — a sign of bile accumulation
Dark urine
Pale stools
Yellowing of the skin or eyes (jaundice)
Pain or tenderness in the upper right abdomen
not medical advice. I don't know anything.