Bigmurph6
Banned
DNP (2,4-Dinitrophenol)
Description
DNP is one of the most controversial drugs in use by anywhere in the world at this time, but is readily available bodybuilders. This agent is not sold for human use is an industrial chemical. Among other things, it is used as
an intermediary for the production of certain dyes for photographic development, as a fungicide, in wood pressure-treatment to prevent rotting, and as an insecticide. It is technically classified as a poison. Although quite incongruous with this list of
strong industrial chemical uses, this chemical was sold during the era of patent medicine as a diet drug for humans. It is this property of dinitrophenol that remains of interest to some
bodybuilders today. Dinitrophenol induces weight loss by uncoupling oxidative phosphorylation, thereby markedly increasing the metabolic rate and body temperature. While this is an
extremely effective way of producing rapid weight loss, there seems to be no ceiling to DNP’s temperature increasing effect. Herein lies perhaps its most dangerous taitit may allow body temperature to rise to level that can
even fatal. Writer Carl Malmberg made
Perhaps one of the earliest and most famous quotes about be damaging, this danger back in the 1930s when he told of a physician
who was literally cooked to death" from using it. This was far from an isolated case, and deaths associated with DNP have continued over the decades. For example, a recent highly publicized story concerns a man that died on Long
Island, NY in 2001 after taking DNP for only four days. The dose used was reported to be 600 mg per day, just three 200 mg capsules.
History
The fat-loss properties of DNP were reportedly first noticed during World War I, when overweight men working with DNP in munitions plants started losing substantial amounts of weight. It did not take very long for this chemical to be identified as the cause. Soon after, it was
packaged as a drug product. By 1935, more than 100,000 Americans had already used “patent medicine” remedies that included DNP. In fact, DNP was the first synthetic drug
that was ever used for weight reduction in this country. While it was available, it was being widely advertised as a new, safe, and effective way to get thin. Popular brand names for DNP included Dinitriso, Nitromet, Dinitrenal and
Alpha Dinitrophenol. At the peak of DNP’s popularity, the drug could be found in pharmacies all across the country.
While the drug may have worked for the intended purpose, it was also introduced at a time before government review and approval of drug safety. In this regard DNP had some very strong shortcomings, and it didn’t take long for
reports of side effects to began pouring in. One such incident involved a dozen women in California who were temporarily blinded by the drug. Numerous reports of DNP-linked cataracts began coming in from as far away as
France and Italy. It was said to be happening with doses as little as 100 mg daily when taken for long periods. Reports of more serious injury, even death, from DNP use followed.
With such highly unfavorable safety reports, the drug was soon pulled. By 1938 it was off the market for good. It has never returned as a medicine for human or animal
consumption. Even so, reports of death associated with DNP use continue to this day.
Author’s Note
I was hesitant to even include a profile of
dinitrophenol in this book, for fear it might entice someone who otherwise may not have known about it to use it. But ultimately I decided it would be better to include the historical information about the drug. The true story of DNP is a scary one and needs to be remembered.
Bodybuilders must understand that the reemergence of underground DNP in the late 1990s was not a revolutionary new achievement in fat loss, but a scary repitition of one of the biggest mistakes of the patent medicine era. It is a drug from a time when an unregulated
market was allowing dangerous chemicals like this to harm the public. The Food and Drug Administration (FDA) exists
today to protect the public from such scenarios. Almost all experts today agree that DNP is a dangerous drug, and is not recommended for weight loss.
Description
DNP is one of the most controversial drugs in use by anywhere in the world at this time, but is readily available bodybuilders. This agent is not sold for human use is an industrial chemical. Among other things, it is used as
an intermediary for the production of certain dyes for photographic development, as a fungicide, in wood pressure-treatment to prevent rotting, and as an insecticide. It is technically classified as a poison. Although quite incongruous with this list of
strong industrial chemical uses, this chemical was sold during the era of patent medicine as a diet drug for humans. It is this property of dinitrophenol that remains of interest to some
bodybuilders today. Dinitrophenol induces weight loss by uncoupling oxidative phosphorylation, thereby markedly increasing the metabolic rate and body temperature. While this is an
extremely effective way of producing rapid weight loss, there seems to be no ceiling to DNP’s temperature increasing effect. Herein lies perhaps its most dangerous taitit may allow body temperature to rise to level that can
even fatal. Writer Carl Malmberg made
Perhaps one of the earliest and most famous quotes about be damaging, this danger back in the 1930s when he told of a physician
who was literally cooked to death" from using it. This was far from an isolated case, and deaths associated with DNP have continued over the decades. For example, a recent highly publicized story concerns a man that died on Long
Island, NY in 2001 after taking DNP for only four days. The dose used was reported to be 600 mg per day, just three 200 mg capsules.
History
The fat-loss properties of DNP were reportedly first noticed during World War I, when overweight men working with DNP in munitions plants started losing substantial amounts of weight. It did not take very long for this chemical to be identified as the cause. Soon after, it was
packaged as a drug product. By 1935, more than 100,000 Americans had already used “patent medicine” remedies that included DNP. In fact, DNP was the first synthetic drug
that was ever used for weight reduction in this country. While it was available, it was being widely advertised as a new, safe, and effective way to get thin. Popular brand names for DNP included Dinitriso, Nitromet, Dinitrenal and
Alpha Dinitrophenol. At the peak of DNP’s popularity, the drug could be found in pharmacies all across the country.
While the drug may have worked for the intended purpose, it was also introduced at a time before government review and approval of drug safety. In this regard DNP had some very strong shortcomings, and it didn’t take long for
reports of side effects to began pouring in. One such incident involved a dozen women in California who were temporarily blinded by the drug. Numerous reports of DNP-linked cataracts began coming in from as far away as
France and Italy. It was said to be happening with doses as little as 100 mg daily when taken for long periods. Reports of more serious injury, even death, from DNP use followed.
With such highly unfavorable safety reports, the drug was soon pulled. By 1938 it was off the market for good. It has never returned as a medicine for human or animal
consumption. Even so, reports of death associated with DNP use continue to this day.
Author’s Note
I was hesitant to even include a profile of
dinitrophenol in this book, for fear it might entice someone who otherwise may not have known about it to use it. But ultimately I decided it would be better to include the historical information about the drug. The true story of DNP is a scary one and needs to be remembered.
Bodybuilders must understand that the reemergence of underground DNP in the late 1990s was not a revolutionary new achievement in fat loss, but a scary repitition of one of the biggest mistakes of the patent medicine era. It is a drug from a time when an unregulated
market was allowing dangerous chemicals like this to harm the public. The Food and Drug Administration (FDA) exists
today to protect the public from such scenarios. Almost all experts today agree that DNP is a dangerous drug, and is not recommended for weight loss.
