High Glucose and low HDL link to Alzheimer's

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JLee

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Interesting read from Boston University about how your glucose and HDL levels in your mid 30s increases your chances of Alzheimer’s.

Lipid and Glucose Levels at Age 35 Associated With Alzheimer’s Disease​

Neuroscience News

16 hours ago

Low HDL and high triglyceride levels in the blood at 35 were associated with an increased risk of developing Alzheimer’s disease later in life. Additionally, higher glucose levels between 51 and 60 were linked to a higher risk of Alzheimer’s.

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Boston University

Living your best life at 35, ignoring cholesterol and glucose levels, may impact your chances of getting Alzheimer’s disease (AD) later in life.

According to researchers from Boston University School of Medicine (BUSM), lower HDL (high-density cholesterol) and high triglyceride levels measured in blood as early as age 35 are associated with a higher incidence of AD several decades later in life.

They also found that high blood glucose measured between ages 51-60 is associated with risk of AD in the future.

“While our findings confirm other studies that linked cholesterol and glucose levels measured in blood with future risk of Alzheimer’s disease, we have shown for the first time that these associations extend much earlier in life than previously thought,” explains senior author Lindsay A. Farrer, Ph.D., chief of biomedical genetics at BUSM.

The researchers believe that although high LDL has been consistently associated with AD risk in many previous studies, the link between HDL and AD was inconclusive, perhaps because most studies examining these relationships were conducted in persons who were 55 years and older at baseline.

This study was conducted using data obtained from participants of the Framingham Heart Study who were examined in approximately four-year intervals throughout most of their adult lives. Correlations of AD with multiple known risk factors for cardiovascular disease and diabetes (including HDL, LDL, triglycerides, glucose, blood pressure, smoking, and body mass index) were measured at each exam and during three age periods during adulthood (35-50, 51-60, 61-70).
 
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