Thoughts on Prozac

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Man that’s how it was for me @Dirtnasty. I was sleeping in til 6am right before I had to leave for work and could barely get out of bed. And I’m not like that at all. I go to bed at 6pm and when 2:15am hits I’m ready to hit the gym
 
Two episodes a year, doesn’t seem frequent enough for a daily med in my very humble opinion. SSRI is a serious drug and you can’t just stop it whenever you want. You have to taper it down or you will have a pretty serious crash.

Is this a general practitioner or a mental health doc?
 
Just my regular doctor I see. So practitioner lol I’m not good with know who is who 😅🤣🤣 I try to avoid the doctors office ahhaha
 
When I left my first wife, “friends” were convinced I must be crazy and basically made me go see a psychiatrist that I subsequently referred to as “Dr. Drugs.” Five minute appointment, prescription for heavy daily dose of Prozac. I took it for a few weeks and felt mentally “dulled”–and that just ain’t me. And it didn’t change any of the choices I had made in my personal life, much to my “friends’” dismay. So I chucked it and never went back. I am subject to periodic bouts of irrational lows, but as someone earlier in this thread noted, modafinil and Armodafinil really work wonders for me when those hit. They are, in large part, dopamine reuptake inhibitors, so it is for me like taking a very low dose of MDMA that persists over a much longer half-life. Combined with very low dose Kratom (500-1000mg), I can be made to be happy chemically! And that’s what I need in those irrationally low moments–something will just get me through back to rationality.

Just my $.02. Could be totally wrong for your particular situation, but for me, a “DRI” works whereas an “SRI” did nothing good.
 
Yeah I was on Prozac for a few months and nothing a few others it just seems serotonin may not be my issue. Of course it was when I was abusing x cuase well that’s what it does
 
I could go into this much further, MAOi monoamine oxidase inhibitors and tricyclics were on the right track but the safety profile got in the way, seleginine works on a different MAOI type B so it can be given w/o the dietary restrictions…If you’ve felt or witnessed Major Unipolar depression that is treatment resistant, well SSRIs will not touch that. These other Meds bind to the inhibitory proteins etc. so there is an increase in Dopamine, NOR-epi, and even serotonin but the Dopamine is the key…especially in a certain part of the brain. Bupropion is more effect at this than Modanifil. It is super complicated and really Prami is a full Dopamine Agonist…caber is not. But prami will make you sick before euphoric…Now we are using Ketamine, Propafol(not in practice, abuse) MDMA…most of the dopamine has to end up in the part of the brain That is the reward system. NA. Oh shit there I go again.Trying to stay layman but I cant even understand what I wrote…I guess the bottom line is Dopamine… In addition, animal studies show that anabolic steroids increase serotonin levels in brain regions involved in mood and dopamine levels in reward-related brain regions . Above all, CBT, Group therapy, Journaling, TRAINING!!!, EATING CORRECTLY!!! add nauseum, are essential for someone with Most mental Illnesses. Making your bed, Taking a shower…having a schedule. SItuational Depressive states are no joke either, like divorce , death of loved one. Oh by the way The catabolic steroids, cortisol, etc. do the opposite. I’m tired…exercise, work, check-in in here, have no time to be depressed or bleed. (JK)
 
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