I did notice that the troches seemed to pump up my estrogen a bit. Interestingly, I have not noticed that yet with the scrotal cream, but having bloods drawn this week, so we will see. I do .5mg Adex E3D anyway, so it should be under control. E2 was 45 last time, and that’s way too low for me. I need it in the 60-70s to grow, feel good, and enjoy sex.