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Which AAS is least impactful on cholesterol?

Andrew0409

Andrew0409

Well-known member
I’m curious on what you guys have found personally or with some scientific backing on the aas that’s least negatively affecting cholesterol and cardiovascular health?

Orals are definitely out of the question as they all tank my HDL and raise my LDL, particularly winny.

I’m guessing it’s probably just straight up testosterone?
 
Primo tanks my LDL pretty quick.

But the more we learn, the more we find that LDL isn’t as important as we once thought. HDL less than 40 is impossible to lay plaque down. Low ldl, low triglycerides, and low ApoB is more important than a high HDL.

Ezetimbe is damn near a perfect ancillary med for those taking AAS.

Pretty much all AAS will affect lipids. But it’s also pretty specific to you. As with most things, run the gear and get bloods done and see how it hits ya.

10 mg ezetimbe at night will do wonders.
 
Andrew0409 said:
I’m curious on what you guys have found personally
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For me… 300 mgs test c and 300mgs mast e a week split into 3 doses with 2-3 ius of hgh 5-6 days a week. Cialis pwo.

Brought all my labs within range.

Full disclosure: 2 mg of ozempic (semaglutide) once weekly scripted from doc.

I’m not @Neuro or @Phill lean but closest I’ve been in years with (for me) great labs.

I had very close advisement from @Neuro and @BBSQ5 and I get labs no less than 5 x a year.
 
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Poppy’s Quarterly Labs Blood Work and testing
I’m ecstatic. Great labs. My bun was high but everything else is heading in the right direction. Fasted Blood glucose is lowest in forever. A1c dropped almost a full point. Lipids are fantastic. Handwritten is last labs 3 months ago. Thanks to @BBSQ5 and @Neuro for their guidance AND more importantly “talking me back from the edge” when im in full on panic mode over this crap. [IMG_0132] [IMG_0131]
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If you have not done so, get a Calcium Score (CAC). This should be done every 5 years I’ve been told.

I needed to get on 10mg of a Statin (Crestor) to help lower mine. 10mg gives you 85% efficacy. It reduced my APOb 23 points.

Eventually PCSK9 inhibits won’t be $500 a month and that will be our best weapon to help remove this “horseman” from the longevity board along with low dose Statins.

I am only using APOb score for monitoring lipids now.
Peter Attia has a lot of great content on this (and this the my source for this info).
It has an actual correlation to CV events.

We should aim to get APOb below 60 and no higher than 90.
 
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