Blood results on TRT - help with high estradiol levels

[DetHH]

I’ve been running 250 test c 1x/week. i feel good at this dosage but i want to get my e2 under control. i’ve never used an AI, serms, or hcg or anything for that matter. not super familiar with it. what do you guys recommend? or if you want to drop a link to an article that’d be cool too.
31 yo. been taking test about 4 years steady now (except came off for a random 6 months and was miserable). i don’t really plan on coming off in the future, unless you guys see something wrong with these results that may make sense to come off for a bit. but what’s the best way to get this e2 under control? thanks brothers

 

[anabolic_geek]

My doctor has me on anastrozole 2x a week at 1mg/dose. Probably a good starting point — I cruise at the exact same altitude. That said: 65 is a pretty good number. You kinda want some elevated e2 because e2 is actually pretty great for gains. My doctor said we probably shouldn’t worry about it unless it ventures into the 120-140 range.

 

[Hulkdad]

No 65 isnt crazy out of control. But i cant say i agree with letting it go to 120 or 140. As most will see some water retention and some sensitive nipples or starting formation of gyno. I like to keep mine right around 50. But if u dont feel like u r holding any water and have no tender nipples i would just let it alone and just keep an eye on it. But if u have gone years without any Ai’s that is good. If u dont have to use them, dont. Simply because of their negative affects on ur lipid panels and bone loss. Having said that if u did decide u wanted to bring ur e2 levels down 20 points or so i would choose exemestane over anostrozole as it doesnt seem to affect ur lipid panels so hard. Although realistically u would need such a small dose of anostrozole i dont think u will have to worry about any negative side affects from ur A1. U would literally only need about a quarter mg a week of anostrozole to bring ur e2 levels down to about 45 or so. And u really should be running some HCG alongside ur test therapy. Even 2 shots a week of hcg at 300iu a shot would do wonders for keeping ur natural test flowing. Because even just 250mg a week of test is enough to suppress ur natural system. Hcg will prevent that.

 

[Bigmurph6]

I always believed that this was a good read on the subject

Estrogen, Prolactin, Progesterone Management + Gynecomastia Prevention & Reversal General

Introduction One of the topics always in question is how to manage estrogen and prolactin levels on cycle. This thread should serve as an informational base to educate users further. This is probably one of the more important topics as the lack of attention to these categories can result in some serious complications. Before we get into managing E2 and prolactin, it’s really important that you understand exactly what they are, their purpose and how they become elevated. Once you have a clear un…

You can type in basically anything into the magnifying glass and it will search the site not Google. Alot of good information it searches by keywords. Search AI, aromatase inhibitor and so on and you will keep getting good write ups.

Good luck and good gains brother

 

[BrandonIron]

E at 65 would have me and my doc upping my AI.
Even so, with test not that elevated, you seem to be pretty sensitive to test aromatizing, so I would definitely seek an AI.
On a run, (500-650 mg test c) my test stays above 3k (the highest the test will show) and free test over 1000, usually 1300. My Estradiol needs to stay below 50, it seems to stick right about 46 with 1 mg of Anostrazole (Arimidex) twice weekly.

If not on a run, just a TRT cruise (200 mg test c weekly) my test stays around 990, and free test around 400.
At this dose my doc has me on .5 mg anastrozole twice weekly, and e stays right on point. Does your doc prescribe AI of any sort? I guess I should ask first, are you in TRT from a clinic or self diagnosed and treating?

 

[Outlawthing]

I’m with hulk daddy on this do have issues do you feel bad or feel like a champion some people run higher i for one do I do take a very small dose of ai but it’s also because I take hcg as well I would get some hcg 250-300 once or twice a week I use my balls as a judge if they are full and hanging once if they Are trying to crawfish and feel empty twice use your body with the bloodwork if you start hcg it may elevate E2 further also your test is borderline high for trt If you take an ai it’s is gonna rise as well also is this the first bloodwork you have or do you have a couple and you are showing an upward trend. Of E2 unless you are having issues a wouldn’t go crazy trying to micromanage your body knows how to do that now if you are having issues we need to look into an ai

 

[Bigmurph6]

It definitely happens I get a increase in e levels after using hcg I had to use some aromasin to get my levels back where I wanted them to be during that run.

 

[Outlawthing]

That is what I use for ai Aromasin it only takes very very little and I’m g2g most people use Adex it seems. Me I would rather kill it than bind it and wait for a mass rebound seemed like adex bothers my BP too maybe just me

 

[Hulkdad]

I look for most TRT clinics to make the switch to aromasin instead anostrozol. There are just to many studies out now showing its superiority over anostrozole. Every study shows clearly a negative affect on cholesterol levels and bone fractures (mainly spine fractures) do to loss of bone mass. And most of the studies done are only 3 to 5 year studies with noticable cholesterol changes and noticable elevation in bone fractures, so imagine the affects arimidex is having on a bodybuilder that has been taking it like candy for 20 to 30 years straight. You see what im trying to say? I stopped using A-dex a few years ago because of these reasons. I now try to use pharmacuticals that are not influenced by the aromatize enzyme and if i do i use aromasin. Remember aromasin and arimidex exhibit their affects in two different ways. Aromasin is a type one third generation and arimidex and letrozole are type 2 third generation, and aromasin def gets the job done more efficiently and with less negative side affects. It just makes sense to use aromasin in front of any other third generation AI on the market. Use as non aromatising compounds when u can and instead of taking mass doses off HCG at a time take smaller but more frequent doses. Im with outlawthing, i never dose more than 300 at a time with HCG.

 

[DetHH]

ive got bloodwork in the past, but never tested for estrogen. t levels would be around 1200 so it is a little elevated this time. and i also drew blood the day before my pin morning so i would assume my levels were even a little lower being day 6. and never had sides like gyno or shrinking testes on test so never took an anti estrogen. but probably should have educated myself more and should of been taking hcg. but that’s what im here for now. appreciate the help brother

 

[DetHH]

why do you say your e needs to stay below 50 when your running 500+?
ive been cruising at 250 for years now. i havent done a run since 2017. i was grabbing too much water my BP would get a little too elevated so i scaled back and feel good at 250.
i was on trt from my physician back in 2016 but stopped cuz of cost. my brother referred me to a doc out where i live now and said he’d get me on arimidex. but i was just going to save the money and cop some from a sponsor here. however, when seeing my doc years ago he never mentioned putting me on ai or hcg? just had me on 200mg test c weekly that was it.

 

[DetHH]

im about to google some of those studies comparing aromasin and arimidex, good looking out with that. spine fractures sound like something we prolly dont need

 

[Hulkdad]

Ill lookback in my research and see if i can find some URLS for u to look up to save u some time ok.

 

[Hulkdad]

Its not that A-dex isnt affective bcuz it def is, it has come a long way since its inception. It now beats out tomoxifin for being the number one go to drug for breast cancer the only problem is the long term sides. And on another note , if u did decide to go with A-dex, i dont think u really have to bargain shop it. They lost their patent years ago, generics are available now. Just find an independent compounding pharmacy are u and u can have them compound u any strengh u want with a generic. I would have them compound an 1/8 mg pill and take one pill about every 3 days and that should bring ur e2 levels down around 20 points or so within a couple weeks. And ur cost on that shouldnt be anymore than about 15 or 20 bucks for a 90 day supply

 

[Hulkdad]

An remember , i wouldnt say ur test levels are really elevated, test levels can fluctuate by a cpl hundred points literally from taking ur labs at 8 instead of 10:30 ot from taking ur last shot later in thr day instead of the morning or waiting till the 6th fay after shot instead of 5th , i mean realisticly u should b splitting ur dose up twice a week because u are already having peaks and valleys on ur blood plasma levels bcuz of the one shot a week protocal u r currently on. So when u get ur lab results keep all of that in mind.

 

[BrandonIron]

I meant to say 60. That’s Because that is the normal range for e2 in men, you don’t want e2 to be above normal range for men.

 

[iosornio1]

My urologist has me on TRT and suggested DIM, only take one capsule 300mgs and it works… it’s a natural supplement tho, it’s has been said that it also helps to keep the prostate healthy yara yara yara… anyways it doesn’t hurt to try , after all it’s not like you going to crash your e2 using it, and if it works for you great right